{"id":2219,"date":"2020-08-06T06:29:24","date_gmt":"2020-08-06T06:29:24","guid":{"rendered":"https:\/\/rise-pfi.no\/?page_id=2219"},"modified":"2023-04-27T06:40:06","modified_gmt":"2023-04-27T06:40:06","slug":"oxypol","status":"publish","type":"page","link":"https:\/\/rise-pfi.no\/en\/focus-areas\/biopolymers-and-biocomposites\/oxypol\/","title":{"rendered":"OxyPol"},"content":{"rendered":"

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Contact:\u00a0Gary Chinga Carrasco<\/a><\/span><\/p>\n

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Oxygenated bioPolymers for biomedical applications<\/strong><\/h3>\n

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An increasing number of patients with chronic wounds have been reported, due to the population\u00b4s increasing age and resultant comorbidities like obesity, diabetes and venous insufficiency. The resulting morbidity and cost for the patient and the society is considerable. Healing of chronic wounds is a complicated process, characterized by elevated inflammatory responses, tissue breakdown, and colonization by predominantly anaerobe bacteria, and cause major challenges for the patient\u00b4s quality of life. Additionally, the extensive, often inappropriate use of antibiotics, for among others wound treatment, has resulted in an increasing resistance of pathogens against antibiotics. The cost implications for the world community are considerable. Hence, appropriate wound treatment requires optimized dressings that can maintain a prolonged moist environment, with adequate mechanical properties in moist conditions, with targeted antibacterial activity, as well as a barrier against wound bacteria. We propose in the OxyPol project optimized nanocellulose-based dressings as an inexpensive therapy option. In addition, alginates and chitosan can be used as additional biopolymers to add mechanical stability and potentially reinforce the antimicrobial properties of functionalized nanocellulose hydrogels and wound dressings. Hence, the OxyPol project will combine novel optimized nanocellulose from wood, alginates and chitosan, to form tailor-made gels for biomedical applications, focusing on wound dressings.\u00a0<\/span><\/p>\n

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Hence, the OxyPol project will combine novel optimized nanocellulose from wood, alginates and chitosan, to form tailor-made gels for biomedical applications, focusing on wound dressings.<\/span><\/p>\n

<\/span><\/p>\n<\/blockquote>\n

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The manufacturing of optimized gels will be upscaled following good manufacturing practices (GMP), and pre-clinical studies will be conducted to confirm the potential of the innovative wound dressing products.<\/span><\/p>\n

 <\/p>\n

[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” parallax__hover=”off” parallax_method__hover=”on” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/rise-pfi.no\/wp-content\/uploads\/2022\/02\/oxypol_web.jpg” alt=”Oxygenated bioPolymers ” title_text=”Nanocellulose” _builder_version=”4.19.4″ _module_preset=”default” border_width_all=”1px” border_color_all=”#747706″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16.0″ _module_preset=”default” custom_padding=”35px||40px|||” global_colors_info=”{}”][et_pb_row _builder_version=”4.17.3″ max_width=”1280px” custom_margin=”|auto|6px|auto|false|false” custom_padding=”2px||10px|||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_text _builder_version=”4.19.2″ header_2_font=”Share Tech||||||||” header_2_text_color=”#747706″ header_2_font_size=”20px” header_3_font_size=”20px” header_3_letter_spacing=”0px” custom_margin=”||11px|||” animation_style=”slide” animation_intensity_slide=”10%” header_3_font_last_edited=”off|desktop” header_3_font_size_last_edited=”off|desktop” global_colors_info=”{}”]<\/p>\n

News in this project<\/strong><\/h3>\n

[\/et_pb_text][et_pb_divider color=”#747706″ _builder_version=”4.16″ max_width=”100%” module_alignment=”left” custom_margin=”||1px||false|false” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.17.3″ _module_preset=”default” max_width=”1280px” custom_padding=”3px|||||” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_post_slider include_categories=”26″ show_arrows=”off” show_pagination=”off” excerpt_length=”150″ show_meta=”off” bg_overlay_color=”rgba(228,226,218,0.83)” use_text_overlay=”off” _builder_version=”4.19.2″ _module_preset=”default” header_text_color=”RGBA(255,255,255,0)” header_font_size=”0px” body_font=”Roboto|700|||||||” body_text_align=”left” body_text_color=”#47403d” body_font_size=”12px” use_background_color_gradient=”on” background_color_gradient_stops=”rgba(255,255,255,0) 0%|rgba(255,255,255,0) 100%” background_color_gradient_start=”rgba(255,255,255,0)” background_color_gradient_end=”rgba(255,255,255,0)” background_image=”https:\/\/rise-pfi.no\/wp-content\/uploads\/2021\/03\/karbonavtrykk19_web.jpg” custom_button=”on” button_text_size=”16px” button_text_color=”#FFFFFF” button_bg_color=”#747706″ button_border_width=”1px” button_border_color=”#e4e2da” button_font=”||||||||” button_alignment=”left” button_custom_margin=”||40px||false|false” positioning=”none” text_orientation=”left” background_layout=”light” width=”100%” min_height=”229px” custom_padding=”45px||0px||false|false” custom_padding_tablet=”180px||0px||false|false” custom_padding_phone=”100px||||false|false” custom_padding_last_edited=”off|desktop” border_width_all=”1px” border_color_all=”#464b11″ global_colors_info=”{}”][\/et_pb_post_slider][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.17.3″ _module_preset=”default” custom_padding=”4px|||||” global_colors_info=”{}”][et_pb_row _builder_version=”4.17.3″ max_width=”1280px” custom_margin=”|auto|6px|auto|false|false” custom_padding=”2px||10px|||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_text _builder_version=”4.19.2″ header_2_font=”Share Tech||||||||” header_2_text_color=”#747706″ header_2_font_size=”20px” header_3_font_size=”20px” header_3_letter_spacing=”0px” custom_margin=”||11px|||” animation_style=”slide” animation_intensity_slide=”10%” header_3_font_last_edited=”off|desktop” header_3_font_size_last_edited=”off|desktop” global_colors_info=”{}”]<\/p>\n

Publications\/Conferences<\/strong><\/h3>\n

[\/et_pb_text][et_pb_divider color=”#747706″ _builder_version=”4.16″ max_width=”100%” module_alignment=”left” custom_margin=”||1px||false|false” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.17.3″ _module_preset=”default” max_width=”1280px” custom_padding=”0px|||||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_toggle title=”2023″ open_toggle_text_color=”#747706″ open_toggle_background_color=”#e4e2da” closed_toggle_text_color=”#747706″ closed_toggle_background_color=”#e4e2da” icon_color=”#464b11″ open_icon_color=”#464b11″ _builder_version=”4.20.4″ _module_preset=”default” title_text_color=”#747706″ title_level=”h3″ title_font=”||||||||” title_font_size=”20px” closed_title_font=”||||||||” hover_enabled=”0″ border_color_all=”rgba(70,75,17,0.45)” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

Journal Articles<\/h3>\n
\n

<\/strong><\/p>\n

Chinga-Carrasco, G<\/a><\/strong>.,\u00a0<\/span>Pasquier, E.<\/a><\/strong>,\u00a0<\/span>Solberg, A.<\/a><\/strong>,\u00a0<\/span>Leirset, I<\/a><\/strong>., (2023)\u00a0 Stevanic J.S., Rosendahl, J., H\u00e5kansson, J. Carboxylated nanocellulose for wound healing applications \u2013 Increase of washing efficiency after chemical pre-treatment and stability of homogenized gels over 10 months.\u00a0<\/span>Carbohydrate Polymers Volume 314<\/em>, 15 August 2023, 120923.\u00a0<\/span>https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0144861723003880<\/a><\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2022″ open_toggle_text_color=”#747706″ open_toggle_background_color=”#e4e2da” closed_toggle_text_color=”#747706″ closed_toggle_background_color=”#e4e2da” icon_color=”#464b11″ open_icon_color=”#464b11″ _builder_version=”4.19.2″ _module_preset=”default” title_text_color=”#747706″ title_level=”h3″ title_font=”||||||||” title_font_size=”20px” closed_title_font=”||||||||” border_color_all=”rgba(70,75,17,0.45)” global_colors_info=”{}”]<\/p>\n

Conferences<\/h3>\n
\n

Gary Chinga-Carrasco, \u201cNanocellulose \u2013 The little giant in the biomedical area\u201d. Invited keynote (In Spanish), NANOCELIA Workshop, June 27th<\/sup>, Girona, Spain.<\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2021″ open_toggle_text_color=”#747706″ open_toggle_background_color=”#e4e2da” closed_toggle_text_color=”#747706″ closed_toggle_background_color=”#e4e2da” icon_color=”#464b11″ open_icon_color=”#464b11″ _builder_version=”4.19.2″ _module_preset=”default” title_text_color=”#747706″ title_level=”h3″ title_font=”||||||||” title_font_size=”20px” closed_title_font=”||||||||” border_color_all=”rgba(70,75,17,0.45)” global_colors_info=”{}”]<\/p>\n

Journal Articles<\/h3>\n
\n

Chinga-Carrasco G<\/a><\/strong>, Johansson J, Heggset EB, Leirset I, Bj\u00f6rn C, Agrenius K, Stevanic JS, H\u00e5kansson J,<\/span>\u00a0<\/span>Characterization and antimicrobial properties of autoclaved carboxylated wood nanocellulose<\/em><\/a>.<\/a> Biomacromolecules 22(7), 2779-2789<\/span><\/p>\n

<\/span><\/p>\n

Knutsen MF, Agrenius K, Ugland H, Petronis S, Haglerod C, H\u00e5kansson J and\u00a0Chinga-Carrasco G<\/strong>.<\/a>\u00a0Oxygenated nanocellulose \u2013 A material platform for antibacterial wound dressing devices<\/a><\/em>. ACS Appl. Bio Mater. 2021, 4, 10, 7554\u20137562<\/span><\/p>\n

<\/span><\/p>\n

Book chapters<\/h3>\n
\n

Chinga-Carrasco G<\/a><\/strong>, Rosendahl J and Catal\u00e1n J,\u00a0<\/span>Nanocelluloses \u2013 nanotoxocology, safety aspects and 3D bioprinting,\u00a0<\/span><\/em>In: Advances in experimental medicine and biology, Springer Nature Switzerland AG (2021), 50 pp<\/p>\n

[\/et_pb_toggle][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Quote” _builder_version=”4.16″ use_background_color_gradient=”on” background_color_gradient_stops=”rgba(255,255,255,0.9) 0%|rgba(255,255,255,0.6) 70%” background_color_gradient_overlays_image=”on” background_color_gradient_start=”rgba(255,255,255,0.9)” background_color_gradient_end=”rgba(255,255,255,0.6)” background_color_gradient_end_position=”70%” background_image=”https:\/\/rise-pfi.no\/wp-content\/uploads\/2021\/01\/about_web.jpg” custom_padding=”0|0px|10vw|0px|false|false” border_color_all=”#747706″ border_width_top=”1px” global_colors_info=”{}”][et_pb_row column_structure=”3_4,1_4″ use_custom_gutter=”on” gutter_width=”2″ custom_padding_last_edited=”on|tablet” _builder_version=”4.16″ background_color=”#ffffff” max_width=”1280px” custom_padding=”30px|60px|40px|60px|false|false” custom_padding_tablet=”|50px||50px||true” custom_padding_phone=”60px|40px|60px|40px|true|true” border_radii=”off|||10px|10px” use_custom_width=”on” custom_width_px=”1280px” global_colors_info=”{}”][et_pb_column type=”3_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.19.2″ text_font=”Roboto|900|||||||” header_2_font=”Share Tech|700|||||||” header_2_font_size=”30px” header_2_letter_spacing=”-1px” header_2_line_height=”1.3em” header_3_font_size=”20px” custom_margin=”||22px|||” header_2_font_size_tablet=”30px” header_2_font_size_phone=”25px” header_2_font_size_last_edited=”on|phone” header_3_font_phone=”Default||||||||” header_3_font_last_edited=”off|phone” global_colors_info=”{}” text_font_size__hover=”14px” text_font_size__hover_enabled=”14px” text_letter_spacing__hover=”0px” text_letter_spacing__hover_enabled=”0px” text_line_height__hover=”1.7em” text_line_height__hover_enabled=”1.7em” text_text_shadow_style__hover=”none” text_text_shadow_style__hover_enabled=”none” text_text_shadow_color__hover=”rgba(0,0,0,0.4)” text_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” link_font_size__hover=”14px” link_font_size__hover_enabled=”14px” link_letter_spacing__hover=”0px” link_letter_spacing__hover_enabled=”0px” link_line_height__hover=”1em” link_line_height__hover_enabled=”1em” link_text_shadow_style__hover=”none” link_text_shadow_style__hover_enabled=”none” link_text_shadow_color__hover=”rgba(0,0,0,0.4)” link_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” ul_font_size__hover=”14px” ul_font_size__hover_enabled=”14px” ul_letter_spacing__hover=”0px” ul_letter_spacing__hover_enabled=”0px” ul_line_height__hover=”1em” ul_line_height__hover_enabled=”1em” ul_text_shadow_style__hover=”none” ul_text_shadow_style__hover_enabled=”none” ul_text_shadow_color__hover=”rgba(0,0,0,0.4)” ul_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” ol_font_size__hover=”14px” ol_font_size__hover_enabled=”14px” ol_letter_spacing__hover=”0px” ol_letter_spacing__hover_enabled=”0px” ol_line_height__hover=”1em” ol_line_height__hover_enabled=”1em” ol_text_shadow_style__hover=”none” ol_text_shadow_style__hover_enabled=”none” ol_text_shadow_color__hover=”rgba(0,0,0,0.4)” ol_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” quote_font_size__hover=”14px” quote_font_size__hover_enabled=”14px” quote_letter_spacing__hover=”0px” quote_letter_spacing__hover_enabled=”0px” quote_line_height__hover=”1em” quote_line_height__hover_enabled=”1em” quote_text_shadow_style__hover=”none” quote_text_shadow_style__hover_enabled=”none” quote_text_shadow_color__hover=”rgba(0,0,0,0.4)” quote_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” text_orientation__hover=”left” text_orientation__hover_enabled=”left” background_layout__hover=”light” background_layout__hover_enabled=”light”]<\/p>\n

Research partners and funding:<\/strong><\/h3>\n

[\/et_pb_text][et_pb_text _builder_version=”4.16″ _module_preset=”default” custom_margin=”||2px|||” global_colors_info=”{}”]<\/p>\n

Research partners<\/h5>\n

[\/et_pb_text][et_pb_text _builder_version=”4.16″ text_font=”||||||||” text_line_height=”2em” header_2_font=”Work Sans|700|||||||” header_2_font_size=”25px” header_2_line_height=”1.5em” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|tablet” custom_padding=”4px|||||” header_2_font_size_tablet=”30px” header_2_font_size_phone=”15px” header_2_font_size_last_edited=”on|desktop” locked=”off” global_colors_info=”{}” header_font_size__hover=”30px” header_font_size__hover_enabled=”30px” header_letter_spacing__hover=”0px” header_letter_spacing__hover_enabled=”0px” header_text_shadow_style__hover=”none” header_text_shadow_style__hover_enabled=”none” header_text_shadow_color__hover=”rgba(0,0,0,0.4)” header_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” header_2_font_size__hover=”26px” header_2_font_size__hover_enabled=”26px” header_2_letter_spacing__hover=”0px” header_2_letter_spacing__hover_enabled=”0px” header_2_line_height__hover=”1em” header_2_line_height__hover_enabled=”1em” header_2_text_shadow_style__hover=”none” header_2_text_shadow_style__hover_enabled=”none” header_2_text_shadow_color__hover=”rgba(0,0,0,0.4)” header_2_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” header_3_font_size__hover=”22px” header_3_font_size__hover_enabled=”22px” header_3_letter_spacing__hover=”0px” header_3_letter_spacing__hover_enabled=”0px” header_3_line_height__hover=”1em” header_3_line_height__hover_enabled=”1em” header_3_text_shadow_style__hover=”none” header_3_text_shadow_style__hover_enabled=”none” header_3_text_shadow_color__hover=”rgba(0,0,0,0.4)” header_3_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” header_4_font_size__hover=”18px” header_4_font_size__hover_enabled=”18px” header_4_letter_spacing__hover=”0px” header_4_letter_spacing__hover_enabled=”0px” header_4_line_height__hover=”1em” header_4_line_height__hover_enabled=”1em” header_4_text_shadow_style__hover=”none” header_4_text_shadow_style__hover_enabled=”none” header_4_text_shadow_color__hover=”rgba(0,0,0,0.4)” header_4_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” header_5_font_size__hover=”16px” header_5_font_size__hover_enabled=”16px” header_5_letter_spacing__hover=”0px” header_5_letter_spacing__hover_enabled=”0px” header_5_line_height__hover=”1em” header_5_line_height__hover_enabled=”1em” header_5_text_shadow_style__hover=”none” header_5_text_shadow_style__hover_enabled=”none” header_5_text_shadow_color__hover=”rgba(0,0,0,0.4)” header_5_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” header_6_font_size__hover=”14px” header_6_font_size__hover_enabled=”14px” header_6_letter_spacing__hover=”0px” header_6_letter_spacing__hover_enabled=”0px” header_6_line_height__hover=”1em” header_6_line_height__hover_enabled=”1em” header_6_text_shadow_style__hover=”none” header_6_text_shadow_style__hover_enabled=”none” header_6_text_shadow_color__hover=”rgba(0,0,0,0.4)” header_6_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” text_letter_spacing__hover=”0px” text_letter_spacing__hover_enabled=”0px” text_text_shadow_style__hover=”none” text_text_shadow_style__hover_enabled=”none” text_text_shadow_color__hover=”rgba(0,0,0,0.4)” text_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)”]<\/p>\n

Oxy Solutions<\/a> is the owner of the OxyPol project. RISE PFI and RISE Bioscience and Materials are the R&D partners.<\/p>\n

[\/et_pb_text][et_pb_text _builder_version=”4.16″ _module_preset=”default” custom_margin=”||2px|||” global_colors_info=”{}”]<\/p>\n

Funding<\/h5>\n

[\/et_pb_text][et_pb_text _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

The project is funded by the Research Council of Norway, through the Nano2021 program.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ _module_preset=”default” header_5_font=”Roboto||||||||” header_5_text_align=”right” header_5_font_size=”14px” global_colors_info=”{}”]<\/p>\n

Project periode: 2020 – 2022<\/strong><\/h5>\n

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RISE PFI<\/a><\/span><\/span>Contact:\u00a0Gary Chinga CarrascoOxygenated bioPolymers for biomedical applicationsAn increasing number of patients with chronic wounds have been reported, due to the population\u00b4s increasing age and resultant comorbidities like obesity, diabetes and venous insufficiency. The resulting morbidity and cost for the patient and the society is considerable. 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